Salmonella infection of macrophages activates nuclear factor kappa B signalling
Duration: 43 secs
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| Description: | RAW 264.7 macrophages expressing the transcription factor RelA-green fluorescent protein (a member of the pro-inflammatory nuclear factor kappa B family of transcription factors) were infected with Salmonella enterica serovar Typhimurium (also expressing green fluorescent protein). |
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| Created: | 2016-09-27 12:03 | ||
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| Collection: | Bryant Media Collection | ||
| Publisher: | University of Cambridge | ||
| Copyright: | Prof. C.E. Bryant | ||
| Language: | eng (English) | ||
| Distribution: |
World
(not downloadable)
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| Keywords: | Macrophage; nucelar factor kappa B; Salmonella; | ||
| Credits: |
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| Categories: |
iTunes - Science - Biology |
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| Explicit content: | No | ||
| Aspect Ratio: | 4:3 | ||
| Screencast: | No | ||
| Bumper: | UCS Default | ||
| Trailer: | UCS Default | ||
| Abstract: | In uninfected cells the green fluorescent transcription factor RelA is restricted to the cytosol (the nucleus remains "empty" of green fluorescent protein). Upon administration of bacteria all the cells become activated (whether or not they are infected) and RelA translocates to the nucleus.. |
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